14. Analysis of Role of Statins on Cardiac Patients with Chronic Kidney Disease and Renal Failure: A Research Analysis
Saad Akmal Bhatti1, Akmal Khurshid Bhatti2 and Ahmed Dilawar Khan3
ABSTRACT
Objective: The objective of our study is to find the role of statins in CVD and those patients who are suffering from renal failure and chronic kidney disease.
Study Design: Comparative / cross sectional study.
Place and Duration of Study: This study was conducted at the Sialkot Medical College and RHC, Dhullanwala, Gujrat from January 2018 to March 2018.
Materials and Methods: The study was conducted at Sialkot Medical College and RHC, Dhullanwala, Gujrat with the permission of ethical committees and concerned departments. For this study the data was collected from 50 patients who were suffering from cardiovascular and kidney diseases. We made two groups of study for this purpose. One group was control group and the other group was suffering from CVD and kidney problems.
Results: The values of analysis of statin therapy in patients shows the comparison between two groups on the basis of functional values. ROC curve explained the specificity and sensitivity of statin therapy in patients.
Conclusion: The results of this study clearly showed that patients of CKD are at increasing risk for CVD. Also, there is significant evidence depicting that patients with CKD get advantage from statin therapy with improvement of CV outcomes. Nevertheless, in patients who are on dialysis and are of stage 5 CKD, the advantages of statin therapy on CV outcomes are less definite, and further large RCTs may be required to explain this substance. Key Words: Chronic, CKD, Statin, Patients, Renal Failure
Citation of articles: Bhatti SA, Bhatti AK, Khan AD. Analysis of Role of Statins on Cardiac Patients with Chronic Kidney Disease and Renal Failure: A Research Analysis. Med Forum 2018;29(5):55-58.