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13.Screening of Young Adults Using HbA1c for Evaluating Pre-Diabetic Status

Huma Ahsan, Moin Ud Din Ahmed and Tooba Khan


Objective: HbA1c is usually used a useful biomarker for monitoring glycemic control but also in predicting and identifying diabetic patients. The objective of this study is to determine the incidence of diabetes in pre-diabetic adults by using HbA1c.

Study Design: Cross Sectional Observational Study

Place and Duration of Study: This study was conducted at the Naz Memorial Hospital Karachi Sindh Pakistan from June, 2019 to December, 2020.

Materials and Methods: After ethical approval, patients attending the medicine clinic of the hospital between 18 and 50 years of age, previously undiagnosed with diabetes, having HbA1c in between 5.4-6.4 and agreed to participate were included. Diabetic patients or with an HbA1c below 5 and above 7 were excluded. SPSS version 23.0 was used for analysis of data. Chi-square and independent t tests were applied between qualitative and quantitative variables keeping p-value of <0.05.

Results: In 100 patients with mean age 33.59 ± 6.68 years, 38 males and 62 females. Mean weight and height was 77.2 ± 12.17 kg and 1.62 ± 0.09 m respectively. 28 patients were between 18.5-24.5 kg/m2 of BMI while 26 between 24.5-30 kg/m2 and 46 were above 30 kg/m2. Mean fasting blood glucose was 110.52 ± 5.63 mg/dl, mean HbA1c 5.87 ± 0.35 %. 54 patients had HbA1c below 6.5 while 46 had above 6.5 but less than 7%.

Conclusion: Significant differences between nationalities, weight, BMI, smoking, family history of diabetes and fasting blood sugar levels were reported in patients having an HbA1c greater than 6.5 %.

Key Words: Pre-diabetes, Glycosylated hemoglobin, Screening

Citation of article: Ahsan H, Ahmed M, Khan T. Screening of Young Adults Using HbA1c for Evaluating Pre-Diabetic Status. Med Forum 2021;32(7):53-57.