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  3. 13. Association Between Periconceptional Folic Acid Deficiency and Occurrence of Skeletal Anomalies in Newborns
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13. Association Between Periconceptional Folic Acid Deficiency and Occurrence of Skeletal Anomalies in Newborns

Riasat Ali Nehra1, Noor ul Mobeen1, Akmal Bhatti2 and Hafsa3

ABSTRACT

Objective: This study was planned to detect the connection among environs component (folic acid inadequacy) and development of Skeletal anomalies during intrauterine life.

Study Design: Case control study.

Place and Duration of Study: This study was conducted at the CLAP Hospital Johar Town and Arif Hospital Kasur from 1st January 2014 to 31st Dec. 2014.

Materials and Methods: It was a suitable sampling, two existing groups  differing in outcome were identified and compared among, 100 sufferers of CLP and  allied skeletal anomalies in neonates age not more than 6 months, in various Hospitals of Lahore. Mothers were asked whether they took folic acid or not during their early pregnancy. Results: The skeletal anomalies number was quite high between mothers having deficiency of folic acid and other vitamins (11% as compared to 2.4% of controls).

Conclusion: Pregnant mothers who have not taken folic acid and other vitamins throughout their early pregnancy developed cleft lip with associated skeletal anomalies in their offspring.

Key Words: Skeletal anomalies, Environmental factors (folic acid and vitamins deficiency).

Citation of articles: Nehra RA, Noor ul Mobeen, Bhatti A, Hafsa. Association Between Periconceptional Folic Acid Deficiency and Occurrence of Skeletal Anomalies in Newborns. Med Forum 2018;29(1):56-59.