12.Efficacy of Mitomycin C and BCG in Urinary Bladder Tumor
Sardar Khatoon Chandio1 , Ghulam Asghar Chandio1 , Aijaz Hussain Memon2 , Altaf Hussain Ghumro4 and Abdul Hakeem Jamali3
ABSTRACT
Objective: To compare the treatments of urinary bladder cancer by Mitomycin C and BCG in order to find out the better drug with good outcomes and least complications.
Study Design: Comparative study.
Place and Duration of Study: This study was conducted at the NORIN Hospital Nawabsah and Urology Department PMC Hospital Nawabshah from July 2016 to June 2018. Materials and Methods: This is a two years study of total 40 patients included 25 (62.5%) males and 15 (37.5%) females suffering from urinary bladder tumor. All the patients were admitted from Urology OPD and emergency investigated and treated accordingly.
Results: Total 40 were included, only 15 (37.5%) were females and 25 (62.5%) were males. Dysuria was common after use of MMC as compared to BCG. Fever was common after use of BCG. Cystitis was little more after use of BCG as compared to MMC. Recurrence was least in case of BCG as compared to MMC use.
Conclusion: It is concluded from our study that BCG is the better drug as compared to MMC because the former has least complications particularly recurrence as compared to MMC use.
Key Words: bladder cancer, BCG, MMC, Cystitis, Dysuria
Citation of articles: Chandio SK, Chandio GA, Memon AH, Ghumro AH, Jamali AH.. Efficacy of Mitomycin C and BCG in Urinary Bladder Tumor. Med Forum 2019;30(4):53-56.