1. Muhammad Imran 2. Manqoosh ur Rehman 3. Tanveer Ahmad Kang

1, 2 & 3. Asstt. Profs. of Orthopaedics, Multan Medical & Dental College, Ibn e Siena Hospital & Research Institute Multan

ABSTRACT

Objectives: To assess the efficacy of intra articular injections in different grades of osteoarthritis of knee.

Study Design: Descriptive study

Place and Duration of Study: This study was conducted at the Department of Orthopedics Railway Hospital Rawalpindi and Ibn-e-Seina Hospital & Research Institute Multan started from June 2008 to June 2012.

Materials and Methods: This study included 90 patients of either sex having mild, moderate and severe grades of osteoarthritis of knee based on radiographic findings. A study proforma was designed in which bio-statics and results of the study were recorded. Five intra-articular injections of hyaluronic acid were given on weekly basis and patients were assessed for pain and functional activity at intervals of 0, 6 and 12 weeks by KSKS, WOMAC and VAS scoring system. These patients were selected consecutively. 

Results: In this study patients with mild and moderate grades of osteoarthritis of knee showed improvement but patients with severe grades of osteoarthritis either showed no response or less improvement.

Conclusion: Intra-articular injection of hyaluronic acid is an effective modality in early stages of osteoarthritis