Search Submit Your Manuscript

Become A Member

  1. Home
  2. June 2023
  3. 11.Relationship of Post-Operative Troponin I with Complications after CABG
Article Image
Admin

11.Relationship of Post-Operative Troponin I with Complications after CABG

Muhammad Farhan Khan1, Iqbal Hussain Pathan1, Naveek Nek1, Jai Parkash2,
Abid Ali Somroo2 and Hosh Muhammad1

ABSTRACT

Objective: To determine the impact of serum level of Troponin-I on the outcome of elective coronary artery bypass surgery.

Study Design: Case control study

Place and Duration of Study: This study was conducted at the Department of Cardiac Surgery PAQSJ Institute of Medical Sciences from 1stJuly 2020 to 30th June 2021.

Materials and Methods: During the defined period 124 patients enrolled in our study divided in two groups based on serum Troponin levels  collected preoperatively and 18 hours after surgery. The patients were divided into two groups, group 1 <10 ng/dl, and group 2, > 10ng/dl of Troponin-I. Both groups were statistically compared for outcome.

Results: There were 84 patients in group 1, 40 patients in group 2. Female gender and history of smoking  showed significant difference among demographic characters between two groups . Intra-operative variable showed no significant differences in use of Internal memory artery usage for grafting, Aortic  cross clamp time and duration of surgery, while there were significant  increase in cardiopulmonary bypass time and number of grafts were observed in group 2. Post-operative variables showed no difference in LCOS, use of IABP, atrial fibrillation red blood  and blood product use, ICU and ward stay and mortality. Nevertheless statistically significant differences were observed for reopening, prolong ventilations and re-intubation in group 2 with High Troponin-I levels.

Conclusion: Troponin levels were raised in all patients after CABG. Raised Troponin-I not related with complications including short term mortality. But the association of reopening for bleeding, prolong invasive ventilations and re-intubation is observed in patients  with high Troponin-I levels. Further study is warranted.

Key Words: CABG (Coronary Artery Bypass Graft), Troponin I, LCOS( Low Cardiac output Syndrome), Bleeding

Citation of article: Khan MF, Pathan IH, Nek N, Parkash J, Somroo AA, Muhammad H. Relationship of Post-Operative Troponin I with complications after CABG. Med Forum 2023;34(6):44-48.