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Citation of article: Sameed QA, Ali F, Farooq L, Mujahid S, Khalid SS, Zafar U. Evaluation of Analgesic Activity of the Ethanolic Extract of Cuscuta Reflexa Stems in Albino Wistar Mice. Med Forum 2023;34(8):38-41.doi:10.60110/medforum.340810.
10. Evaluation of Analgesic Activity of the Ethanolic Extract of Cuscuta Reflexa Stems in Albino Wistar Mice
Qurat ul Ain Sameed1, Fizzah Ali2, Lubna Farooq3, Sumreen Mujahid3, Syed Saqib Khalid2 and Urooj Zafar3
ABSTRACT
Objective: The goal of the current study is to assess the palliative / analgesic action of Cuscuta Reflexa stem extract in comparison with standard drug Morphine.
Study Design: A Experimental study
Place and Duration of Study: This study was conducted at the University of Karachi in Karachi, Pakistan, for nine months from February 2020 to November 2020.
Materials and Methods: The pain- relieving effect was assessed by using Tail Flick method to induce pain in the albino mice and the latency period was noted. Four groups of animals were made. Each group has seven albino mice, viz. control, standard drug and extract-treated with two different dosage assemblies.
Results: Cuscuta Reflexa contributes a dose-dependent pain-relieving effect using Tail Flick method in Albino mice.
Conclusion: The outcomes represent Cuscuta Reflexa extract has important pain-relieving constituents. These outcomes support the traditional use of Cuscuta Reflexa for the management of pain using morphine.
Key Words: Cuscuta Reflexa, pain, palliative/ analgesic, morphine, albino mice