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Use of Sodium Tetradecyl Sulphate in the Treatment of Venous Malformation of Oral Cavity

Abubakar Saddique, Jehan Alam, Zubair Ahmed, Shoaib Mirza,
Gobind Rai and Arsalan Tariq

ABSTRACT

Objective: To observe the efficacy of sodium tetradecyl sulphate as sclerosing agent in venous malformation of
oral cavity.

Study Design: Cross sectional study

Place and Duration of Study: This study was conducted at the Department of Oral and Maxillofacial Surgery, Jinnah Postgraduate Medical Centre from September 2023 to March 2024 over six months.

Methods: The clinical efficacy of the treatment was evaluated based on the following grades: "No response," indicating no change in size post-injection; "Mild response labeled as 25% reduction in lesion size, moderate response labeled as 50% reduction in lesion size, good response 75% and 100% reduction considered as complete response.

Results: Regarding response of treatment in 8% of patients no response was observed, moderate response was observed in 36% of cases, 23% patients showed good response and in 33% complete response was observed. Edema was the most common complication among the study patients, in 50.8% patients.

Conclusion: Sclerotherapy with sodium tetradecyl sulfate (STS) is widely recognized as an effective treatment for venous malformations (VMs), boasting minimal side effects and yielding favorable results in many cases.

Key Words: Venous malformation, Sodium tetradecyl sulphate, Oral cavity, Sclerotherapy, Treatment response

Citation of article: Saddique A, Alam J, Ahmed Z, Mirza S, Rai G, Tariq A. Use of Sodium Tetradecyl Sulphate in the Treatment of Venous Malformation of Oral Cavity. Med Forum 2024;35(10):3-6. doi:10.60110/medforum.351001.