1. Comparative Activity of Vaccinium Macrocarpon and Antibiotics in Pregnancy
Saima Bukhari1, Wajid Ali1 and Zakia Subhan2
ABSTRACT
Objective: The objective of this study was to assess the in vitro activity of vaccinium macrocarpon in comparison with antibiotics in pregnancy.
Study Design: Experimental study
Place and Duration of Study: This study was executed in the Pathology Department of Ayub Medical College and outdoor clinics of Ayub Teaching Hospital, Abbottabad from May 2020 to December 2020.
Materials and Methods: In this in vitro study, a total of 72 symptomatic pregnant ladies of urinary tract infection were screened and out of these 60 pregnant ladies in their 2nd and 3rd trimester were selected after their positive urine cultures for E-coli. Patients in Group A were given vaccinium macrocarpon for 10 days, while patients in Group B and C were given Cefixime and Co-amoxiclav for the period of 5 days respectively. Sensitivity test of vaccinium macrocarpon and antibiotics was done against the test bacteria for comparison. Zone of inhibition was measured
in mm.
Results: The p-values of Shapiro-Wilk tests of Vaccinium macrocarpon, Cefixime and Co-amoxiclav are 0.075, 0.435 and 0.186 respectively, which highlighted the measures following the normal distribution. The mean value presented with Vaccinium macrocarpon was 19.47±1.37. The mean value presenting with Cefixime was 22.41±1.26.The mean value presenting with Co-amoxiclav was 21.75±1.09. The p-value between Vaccinium macrocarpon and Cefixime is 0.000. The p-value between Vaccinium macrocarpon and Co-amoxiclav is 0.000 whereas Cefixime and Co-amoxiclav is 0.08.
Conclusion: The results showed that antibiotics are superior to vaccinium macrocarpon in treating urinary tract infection in pregnant ladies.
Key Words: Urinary tract infection, E-coli, Vaccinium macrocarpon, Cefixime, Co-amoxiclav
Citation of article: Bukhari S, Ali W, Subhan Z. Comparative Activity of Vaccinium Macrocarpon and Antibiotics in Pregnancy. Med Forum 2021;32(3):2-5.