9. To Compare the Mean Corneal Endothelial Cell Count Between the Sodium Hyaluronate 1% VS Hydroxy Propyl Methyl Cellulose (HPMC) in Patients Undergoing Phacoemulsification
Naresh Kumar, Rabia Chaudhry, Imran Ali, Wejai Kumar, Nasar Qamar khan and
Objective: To determine mean corneal endothelial cell count between the sodiumhyaluronate1% vs. Hydroxy propyl methyl cellulose (HPMC) in patients undergoing phacoemulsification.
Study Design: Randomized control trial (RCT).
Place and Duration of Study: This study was conducted at the Ophthalmology Department, Jinnah Postgraduate Medical Centre; Karachi from 1st April, 2018 to 30th September, 2018.
Materials and Methods: There were 61 patients having cataract were included in this study. Patients were randomly allocated into two groups. Patients in group 1 were treated with sodium hyluronate 1% and group 2 was treated with Hydroxy-propyl-methyl-cellulose 2%. All the patients were underwent phacoemulsification. Foldable intraocular lens (IOL) was implanted in all cases. Measurements of the endothelial cell count were made 1 day before the surgery and at the end of 6 weeks. All the data was entered on the pre-designed proforma.
Results: There were 28(45.2%) male and 34(54.8%) female. Reduction in mean endothelial cell count was significantly high in group 2 as compare to group 1 (p=0.0005).
Conclusion: In conclusion, our study suggests that 2% Hydroxypropyl methylcellulose, compared with sodium hyaluronate 1%, is superior in protecting the corneal endothelial cells.
Key Words: Phacoemulsification, Corneal endothelial cell, Hydroxy propyl methyl cellulose, sodium hyaluronate
Citation of article: Kumar N, Chaudhry R, Ali I, Kumar W, Khan QN, Riaz A.To Compare the Mean Corneal Endothelial Cell Count between the Sodium Hyaluronate1% vs. Hydroxy propyl Methyl cellulose (HPMC) in Patients Undergoing Phacoemulsification. Med Forum 2019;30(11):31-34.