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9. Diagnostic Accuracy of Ultrasound Breast Masses Taking Histopathology as Gold Standard


Zafar Tanveer Ahmed1, Saima Ameer3, Madeeha Tanveer3 and Fareeha Tanveer3




Objective: To determine the diagnostic accuracy of ultrasound in differentiating benign and malignant breast

masses taking histopathology as gold standard.

Study Design: Cross sectional validation study


Place and Duration of Study: This study was conducted at the Department of Radiology, Lahore General Hospital, Lahore from February 2019 to August 2019.


Materials and Methods: Patients between the ages of 20 to 70 years referred to Radiology department from surgical OPD with history of breast lump. Ultrasound was done in radiology department with high frequency linear probe 7. 5 MHz of Toshiba Xario 200. Findings were noted. FNAC was done and samples were sent for histopathology. The data was analyzed in SPSS v. 21.


Results: The mean age of females was 47.88±11.29 years. There were 121 (66.4%) females belonged to low socioeconomic status, 55 (30.2%) females belonged to middle class while 6 (3.3%) females belonged to high class. In total sample, 147 (80.8%) females were married while 35 (19.2%) were unmarried. There were 79 (43.4%) were nulliparous while 103 (56.6%) had 1 or more children. The mean duration of diagnosis was 12.94±2.36 moths. The mean lump size was 37.84±15.87 mm. In this study, the Sensitivity of ultrasound was 94.1%, specificity was 89.3%, PPV was 77.4%, NPV was 97.5% and diagnostic accuracy was 90.7%.


Conclusion: Thus the ultrasound is accurate enough that it can be applied as first line diagnostic tool for differentiation of malignant breast lesions from benign lesions.


Key Words: Breast Malignancy, Ultrasound, Mammography, Fine Needle Aspiration Cytology, Histopathology


Citation of article: Ahmed ZT, Ameer S, Tanveer M, Tanveer F. Diagnostic Accuracy of Ultrasound in Differentiating Benign and Malignant Breast Masses Taking Histopathology as Gold Standard. Med Forum 2019;31(4):36-39.