7. Sickle Cell Trait and Disease in Anaemic Patients, Visiting Health Care Centre, KFU, Al Hasa
Hussain Mohammed Alhiwaishil1, Ashok Kumar2, Ali Hussain Alrufayi3, Ali Abdulkarim Alsuliman4 and Chetan Lal2
ABSTRACT
Objective: To determine the frequency of sickle cell trait and disease in anaemic patients of Al Hasa.
Study Design: Descriptive / cross-sectional study
Place and Duration of Study: This study was conducted at the At health Care Centre, King Faisal University, Al Hasa, from June to November 2016.
Materials and Methods: Anaemic patients, diagnosed by blood complete picture,were included in the study.Total 638 anaemic patients were investigated for sickle cell trait and disease, which consisted of 230 children (100 males and 130 females), and 408 adults (210 males and 198 females). The blood samples of these patients were analyzed by using both, the sickle cell screening kit and the haemoglobin electrophoresis.The data were analysd by using SPSS 18.
Results: 80 (12.5%) out of 638 investigated patients were positive for sickle cell trait, among which 32 were children (10 males and 22 females) and 48 were adults (26 males and 22 females). 20(3.1%) out of 638 investigated patients were positive for sickle cell disease, among which 6 were children (1 male and 5 females) and 14 were adults (10 males and 4 females).
Conclusion: We found a significant frequency of sickle cell trait and disease in anaemic patients of our region Al Hasa, which indicates the urgent need of screening and counselling programs in this region to prevent further transmission of this familial disorder to new generations.
Key Words: Anaemia, frequency, sickle cell disease, sickle cell trait
Citation of articles: Alhiwaishil HM, Kumar A, Alrufayi AH, Alsuliman AA, Lal C. Sickle Cell Trait and Disease in Anaemic Patients, Visiting Health Care Centre, KFU, Al Hasa. Med Forum 2019;30(5):27-30.