6. Does Antibiotic Coated Polyglactin Helps in Reducing Surgical Site Infection in Clean Surgery?
Rufina Soomro, Nadeem Khurshaidi, Syed Sheeraz ur Rahman and Rabab Hassan
Objective: To compare the frequency of surgical site infections in plain polyglactin versus Antibiotic (Triclosan) coated polyglactin suture material in benign clean breast diseases.
Study Design: Randomized Controlled Trial
Place and Duration of Study: This study was conducted at the Department of General Surgery, Breast Unit, Liaquat National Hospital. Karachi from Sep 2015 till Mar 2016.
Materials and Methods: A total number of 378 patient meeting in the inclusion criteria and consenting for the enrolment in the study for minor clean breast surgeries were randomly divided into two groups. In one group the wounds were closed subcutaneously with plain polyglactin suture, while in the second group triclosan coated polyglactin suture was used. The wounds were examined on the 3rd, 7thand 30th day post operatively, for signs of superficial surgical site infection (SSI). There was no use of antibiotics post-operatively. However, treatment was offered to patients who develop SSI.
Results: The frequency of SSI in the study group (triclosan coated polyglactin) was 5.8%(11 of 189 patients) while in the control group it was 3.7%(7 of 189). The difference between the two groups was not statistically significant (P-value= 0.507).
Conclusion: The study did not demonstrate a statistically significant reduction of superficial surgical site infection when triclosan coated polyglactin suture was used in clean wounds. More studies need to be conducted with larger sample size to look at its effects on other wound categories.
Key Words: Antibiotic coated polyglactin, triclosan coated polyglactin, Surgical Site Infection, Clean Wounds
Citation of article: Soomro R, Khurshaidi N, Rahman SS, Hassan R. Does Antibiotic Coated Polyglactin Helps in Reducing Surgical Site Infection in Clean Surgery? Med Forum 2017;28(2):23-26.