25. Frequency of Thyroid Dysfunction in Pregnant Women Visiting Outpatient Department of a Tertiary Care Hospital of South Punjab
Zoya Khan, Shumaila Kiran and Muzimmal Zulfquar Bhatti
ABSTRACT
Objective: To determine the frequency of thyroid dysfunction in pregnant healthy woman.
Study Design: Cross sectional study.
Place and Duration of Study: This study was conducted at the out-patient Department of Gynecology and Obstetrics, Nishtar Hospital, Multan from May 2015 to May 2016
Materials and Methods: Four hundred fifty-one healthy pregnant women visiting out-patient department of Gynecology and Obstetrics were included in this study and serum TSH test was done in all patients enrolled in study. The patients with deranged TSH test were further assessed by free T3 and T4 levels from central lab Nishtar hospital Multan. All the data was entered and analyzed by using SPSS v-20.
Results: Our study included a total of 451 healthy pregnant ladies who met inclusion criteria of our study. Mean age of our study cases was noted to be 27.87 ± 4.76 years while majority of our study cases i.e. 289 (64.1%) belonged to age group ranging from 20 - 30 Years. Mean Parity of our study cases was 2.88 ± 0.99, our study results have shown that majority of our study cases i.e. 325 (72.1%) had parity equal or less than 3. Mean gravidity was 3.96 ± 0.95 and majority of these ladies i.e. 307 (68.1%) had parity ranging from 1 – 4. Mean gestational age of our study cases was 20.25 ± 4.30 weeks (range 13 – 26 weeks). Euthyroid was seen in 303 (67.2 %) of our study cases, of the remaining 148 (32.8%) having thyroid dysfunction, subclinical hypothyroidism was seen in 94 (20.8 %) and subclinical hyperthyroidism was seen in 54 (12.0%) of our study cases.
Conclusion: High frequency of thyroid dysfunction was noted in our study. Subclinical hypothyroid was significantly associated with increasing age, parity more than 3 and gestational age. Subclinical hyperthyroid was also significantly associated with age. Our study results suggest that all pregnant ladies should be screened for these thyroid hormones to overcome these related adverse outcomes. This will help to decrease disease morbidity and improve quality of life of our patients.
Key Words: Thyroid dysfunction, Subclinical hypothyroid, euthyroid
Citation of article: Khan Z, Kiran S, Bhatti MZ. Frequency of Thyroid Dysfunction in Pregnant Women Visiting Outpatient Department of a Tertiary Care Hospital of South Punjab. Med Forum 2017;28(11):101-104.