20. Prevalence, Hematological Picture and Blood Glucose in Thyrotoxicosis at Sialkot
Mansoor Hassan1, Saleh Muhammad1, M. Awais3, and Muhammad Sabir2
Objective: To Study the Prevalence, Hematological Picture and Blood Glucose in Thyrotoxicosis at Sialkot.
Study Design: Descriptive / observational Study.
Place and Duration of Study: This study was conducted at the Idris Teaching Hospital Sialkot and Allama Iqbal Memorial Hospital Sialkot from January 2014 to April 2017.
Materials and Methods: This study included 100 newly diagnosed patients of thyrotoxicosis registered at Idris Teaching Hospital Sialkot and Allama Iqbal Memorial Hospital Sialkot. Subjects were examined for their signs and symptoms as well as their clinical and family history of thyroid disorders. Their blood samples were drawn and preserved at -80C. They were clinically categorized into hyperthyroidism by thyroid function test utilizing RIA. Patients having clinically visible enlarged swelling in front of neck were subjected to 99Tc Pertechnetate thyroid imaging. The Hematological Picture and Blood Glucose were also recorded. Our study included subjects of all ages and both genders. An informed consent was obtained from each individual participant and all the subjects were interviewed for collecting demographic and disease data on designed Performa. Initial screening included complete thyroid profile to identify thyrotoxicosis. Permission of ethical committee was also taken.
Results: In our study the prevalence of the patients of Thyrotoxicosis was higher (31 %) n=31 at the age of 41-50 years as compared to other age groups as shown in table no. 01 . Female patients were (90%) n=90 and (10%) n=10 male as shown in table no .01. The patients of Thyrotoxicosis from rural area were (68%) n=68 & (32%) n=32 from urban population as shown in table no. 02. Fasting blood glucose was 108.62±31.47 mg/dl in male and 142.5±64.68 mg/dl in female. Random blood glucose was 200±25.27 mg/dl in male and 250±54.24 mg/dl in female. Glycosuria was present in 1 (1%) male and 4 (4%) in female. Proteinuria was absent in both genders as shown in table no. 03. Hemoglobin was 7-10 (gm/dl) in (4%) 4 male and 45 (45%) in female, 11-12gm/dl in (4%)4 male and (22%)22 in female, more than 12gm/dl (2%) 2 in male and (23%) 23 female. TLC was less than 4000cmm 1 (1%) in male and 1 (1%) in female, 4000-11000cmm (7%) 7 male and (85%) 85 female, more than 11000cmm was in (2%) 2 male and 4 (4%) in female. ESR was 15-30mm after 1st hour (6%) 6 male and (66%) 66 in female, more than 30mm after 1st hour was (4%) 4 in male and (24%) 24 in female as shown in table no. 04.
Conclusion: Public awareness about the dietary iodine consumption is mandatory in our region, so as to overcome the increased prevalence of the thyroidal dysfunction in our population. Furthermore, hyperthyroid state is more common in our population.
Key Words: Thyrotoxicosis, Hematological Picture and Blood Glucose.
Citation of articles: Hassan M, Muhammad S, Awais M, Sabir M. Prevalence, Hematological Picture and Blood Glucose in Thyrotoxicosis at Sialkot. Med Forum 2017;28(9):79-82.