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  3. 19. Comparative Efficacy of Hyoscine- N-Butylbromide versus Drotaverine Hydrochloride in the Augmentation of Labor
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19. Comparative Efficacy of Hyoscine- N-Butylbromide versus Drotaverine Hydrochloride in the Augmentation of Labor

 

Azra Shuaib1, Bushra2, Ambreen Ghori2, Asad Ali Zardari4, Rozina Mujeeb Sahito5 and

 

 

 

 

Rekha3

 

 

 

 

 

 

ABSTRACT

 

 

 

 

Objective: To compare the efficacy of Hyoscine-N-butylbromide versus drotaverine hydrochloride in the augmentation of labor.

 

Study Design: Double-blind, randomized controlled trial study

 

Place and Duration of Study: This study was conducted at the Gynecology Unit-I, Liquate University Hospital Hyderabad for the period of one year from February 2018 to January 2019.

 

Materials and Methods: This study was conducted on 270 women to compare the efficacy of Hyoscine-N-butyl bromide versus drotaverine hydrochloride in the augmentation of labor Gynecology Unit-I Liquate University Hospital Hyderabad. Women of reproductive age group between 18-35 years and gestational age between 37-40 weeks were included. All the data was analyzed in SPSS version 22.0.

 

Results: The average age of the patients was 21.45±5.42 years. Efficacy was significantly high in the drotaverine hydrochloride group than the Hyoscine-N-butylbromide group (73% vs. 41.8% p=0.0005). Conclusion: Drotaverine hydrochloride appears to be effective in accelerating the first stage of labor.

 

Key Words: Active management of labor, Drotaverine hydrochloride, the first stage of labor, Hyoscine-N-butylbromide

 

 

Citation of article: Shuaib A, Bushra, Ghori A, Zardari AA, Sahito RM, Rekha. Comparative Efficacy of Hyoscine-N-Butylbromide versus Drotaverine Hydrochloride in the Augmentation of Labor. Med Forum 2021;32(1):76-80.