18. Histopathological Findings in Malignant and Benign Parotid Glands Tumors
Sadia Yaseen1, Ayesha Khalid2, Rizwan Saghir Chatha3 and Burhan-ul-Haq4
ABSTRACT
Objective: To understand the pathology of benign and malignant salivary gland tumors in parotid glands and its relation with gender.
Study Design: Cross-sectional-analytical study.
Place and Duration of Study: This study was conducted at the Department of Pathology, Government Said Mitha Teaching Hospital Lahore from 11st August 2017 to 15th September 2019.
Materials and Methods: Sixty-two parotid glands neoplastic lesions were included. The specimens consisted of incisional biopsies, partial parotidectomy and complete parotidectomy. All the samples were fixed in 10 percent formalin, processed, sectioned and stained according to standard protocol. Slides were analyzed by the authors and categorized according to the historical tumor class of the World Health Organization and were reviewed for descriptions of cellular morphology, encapsulation, perineural and vascular structures and the surrounding environment.
Results: The age of patients was 13-74 years. Twenty-five (40.3%) patients were male and 37(59.57%) patients included were female. Forty-four (70.96%) cases were classified as benign tumors and 18 (29.03%) cases as malignant tumors. In benign lesionspleomorphic adenoma was most common found in 36 (81.82%) patients and among malignant lesions Mucoepidermoid Carcinoma was most frequent found in 11 (61.11%) patients. No significant difference was found for distribution of benign, malignant and their subtypes between males and females
Conclusion: Parotid gland tumors are relatively less common and they exhibit a wide variety of microscopic appearances even within one particular lesion. Accurate diagnosis with histological correlation is essential as parotid gland neoplasms have diverse clinical and prognostic outcomes.
Key Words: Salivary gland tumor, Parotid glands tumor, Neoplastic lesion
Citation of article: Yaseen S, Khalid A, Chatha RS, Haq B. Histopathological Findings in Malignant and Benign Parotid Glands Tumors. Med Forum 2020;31(9):76-79.