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15.Frequency of Low HDL in Young Patients in Acute Myocardial Infarction

Kashif Ali Hashmi, Muhammad Saeed Khalid and Hafiz Abdul Kabir

ABSTRACT

Objective: To evaluate the frequency of low HDL in young patients in acute myocardial infarction.

Study Design: Cross-sectional study

Place and Duration of Study: This study was conducted at the Department of Cardiology Ch. Pervaiz Elahi Institute of Cardiology, Multan from Sep, 2019 to Feb, 2020 for a period of 05 months.

Materials and Methods: Patients with acute myocardial infarction admitted within 24 hours were included. Lipid-lowering therapy, diabetes mellitus, and hypothyroidism were regarded as exclusion criteria. Demographic variables and the complete history of the patients were taken. 5 mL of venous blood was taken from patients during 24 hours of AMI and was immediately transferred to plain tubes. The samples were analyzed using calorimetric kit methods for the detection of High-density lipoprotein (HDL). HDL was considered deranged if found <40mg/dL in males or <50mg/dL in females.

Results: The age of the patients ranges from 20 to 35 years with the mean age of 28 ± 6.32 years. Among these 56.6% were males and 43.4% were females. Blood serum of 28 patients 46.6% out of 60 revealed low levels of high-density lipoprotein. Among these 28 patients, 20% were females and 26.6% were females. The comparison of percentages using chi-square revealed no statistically significant difference in the male and female groups (p>0.05). However, the overall percentage analysis shows significantly low levels of HDL in a study population of Acute myocardial infarction (p<0.05).

Conclusion: There is a high frequency of low HDL in young patients presenting with acute myocardial infarction.

Key Words: Acute myocardial infarction, Dyslipidemia, High-density lipoprotein

Citation of article: Hashmi KA, Khalid MS, Kabir HA. Frequency of Low HDL in Young Patients in Acute Myocardial Infarction. Med Forum 2021;32(10):67-70.