14. Frequency of Hypothyroidism in Patient With Hepatitis C Infection Attending A Tertiary Care Hospital
Hafeez Yaqoob, Shahid Karim, Muhammad Tanweer Khalid, Hamid Ali, Afsheen Faryal and Ghulam Mujtaba
ABSTRACT
Objective: To determine the frequency of Hypothyroidism in patient with Hepatitis C infection
Study Design: Cross sectional study
Place and Duration of Study: This study was conducted at the Department of Gastroenterology, Liaquat National Hospital, Karachi from Oct 2018 to April 2019.
Materials and Methods: All patients who met the inclusion criteria and visited the Department of Gastroenterology at Liaquat National Karachi Hospital were included in the report. After acceptance by ethics and informed and written consent. Brief history was taken, clinical examination was done and blood sample was sent for Thyroid stimulating Hormone (TSH), free T4 (FT4) to access the outcome i.e. frequency of Hypothyroidism in patient with Hepatitis C infection.
Results: 97 patients with Hepatitis C infection were included. 46 patients of which were (i.e., 47.4%) males & 51 patients (i.e., 52.6%) were female patients with the age of 33.96+7.247 years. Hypothyroidism was seen in 25 patients (25.8%).
Conclusion: In 25.8 percent of patients with HCV infection, HCV infection itself induces biochemical thyroid dysfunction prior to treatment.
Key Words: Hepatitis C virus, hypothyroid, chronic hepatitis C
Citation of article: Yaqoob H, Karim S, Khalid MT, Ali H, Faryal A, Mujtaba G. Frequency of Hypothyroidism in Patient with Hepatitis C Infection Attending A Tertiary Care Hospital. Med Forum 2020;31(12):63-67.