Become A Member

  1. Home
  2. April 2018
  3. 12. Comparison of 2% Lignocaine with 50% Magnesium Sulfate in Reducing the Hemodynamic Stress Responses to Laryngoscopy and Endotracheal Intubation
Article Image
Admin

12. Comparison of 2% Lignocaine with 50% Magnesium Sulfate in Reducing the Hemodynamic Stress Responses to Laryngoscopy and Endotracheal Intubation

Saima Javaid Joyia, Tariq Bashir and Iqra Batool

ABSTRACT

Objective: The comparison of 2% lignocaine with 50% magnesium sulfate in reducing the hemodynamic stress responses to laryngoscopy and endotracheal intubation in ASA (American Society of Anesthesiologists) grade I and II patients.

Study Design: A randomized control trail.

Place and Duration of Study: This study was conducted at the Anaesthesia department of Bahawal Victoria Hospital, Bahawalpur from July, 2017 to December, 2017.

Materials and Methods: Ninety two patients were divided randomly into two equal groups, Group-L for lignocaine and Group-M for magnesium sulfate. Age and weight of every patient was documented. Heart rate, systolic and diastolic blood pressures and mean arterial pressure were recorded before and after pre-medication, after injecting the drugs under study and at 1, 3 and 5 minutes after intubation. Variables were compared between the two groups and t-test was applied. SPSS v.23 was used to analyze the data. P value was taken as <0.05.

Results: The mean heart rate was significantly high in group-L at 1 minute (p=0.006), 3 minute (p=<0.001) and 5 minute (p<0.001) after the intubation. Mean systolic blood pressure, diastolic blood pressure and mean arterial pressure were also high in group-L at 1 minute, 3 minute and 5 minute after the intubation with statistically significant difference (p<0.001).

Conclusion: It was hereby concluded that significantly better and well-sustained control over hemodynamic stress responses to laryngoscopy as well as tracheal intubation, is obtained by the use of magnesium sulfate, as compare to lignocaine. This shows that magnesium sulfate is superior to lignocaine in offsetting the hemodynamic stress responses to laryngoscopy as well as endotracheal intubation.

Key words: 2% Lignocaine, 50% magnesium sulfate, hemodynamic, stress responses, laryngoscopy, endotracheal intubation

Citation of articles: Joyia SJ, Bashir T, Batool I. Comparison of 2% Lignocaine with 50% Magnesium Sulfate in Reducing the Hemodynamic Stress Responses to Laryngoscopy and Endotracheal Intubation. Med Forum 2018;29(4):50-54.